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Technical Data |
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I0797-76 |
(-)-Indolactam V |
300ug |
| Molecular Biology | Storage: -20°CShipping: Blue Ice |
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Moderately potent indolactam activator of protein kinase C; Kd for binding at the PDBu site is in the micromolar range. Weak tumor promoter. Solubility: Soluble in DMSO or ethanol Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. CAS Number: 90365-57-4 Molecular Formula: C17H23N3O2 Molecular Weight: 301.38 |
Purity: ~99% (HPLC and TLC) Form: Supplied as an off-white powder Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Fujiki, H., et al. "Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin." Gann 75:866-870 (1984). 2. Heikkila, J. and Akerman, K.E.O. "(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells." Biochem. Biophys. Res. Comm. 162:1207-1213 (1989).
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