Technical Data
I0797-76
(-)-Indolactam V
300ug
Molecular Biology Storage: -20CShipping: Blue Ice
Moderately potent indolactam activator of protein kinase C; Kd for binding at the PDBu site is in the micromolar range. Weak tumor promoter.

Solubility:
Soluble in DMSO or ethanol

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

CAS Number:
90365-57-4

Molecular Formula:
C17H23N3O2

Molecular Weight:
301.38
Purity: ~99% (HPLC and TLC)
Form: Supplied as an off-white powder

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Fujiki, H., et al. "Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin." Gann 75:866-870 (1984). 2. Heikkila, J. and Akerman, K.E.O. "(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells." Biochem. Biophys. Res. Comm. 162:1207-1213 (1989).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.