Technical Data
I0798
Indolmycin (Antibiotic PA 155A)
1mg
Biochemicals Storage: -20CShipping: Blue Ice
Indolmycin is a highly selective antibiotic which acts as a tryptophan anti-metabolite. Recent research has shown that indolmycin is active against Mycobacteria and Helicobacter pylori and can stimulate transcription in Escherichia coli.

Purity: >99% by HPLC, mixture of diastereoisomers

Solubility: Soluble in ethanol, methanol, DMF or DMSO.

Related to: Pimprinine

CAS Number:
21200-24-8

Molecular Formula:
C14H15N3O2

Molecular Weight:
257.3
Source: Streptomyces sp.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Indolmycin resistance of Streptomyces coelicolor A3(2) by induced expression of one of its two
tryptophanyl-tRNA synthetases. Kitabatake M. et al. J. Biol. Chem. 2002, 277, 23882.
2. Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori
agent. Hasuoka A. et al. Chem. Pharm. Bull. 2001, 49, 1604.
3. Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli.
Bogosian G. et al. J. Bacteriol. 1983, 153, 1120.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.