Technical Data
I0798
Indolmycin (Antibiotic PA 155A)
1mg
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Technical Data |
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I0798 |
Indolmycin (Antibiotic PA 155A) |
1mg |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Indolmycin is a highly selective antibiotic which acts as a tryptophan anti-metabolite. Recent research has shown that indolmycin is active against Mycobacteria and Helicobacter pylori and can stimulate transcription in Escherichia coli. Purity: >99% by HPLC, mixture of diastereoisomers Solubility: Soluble in ethanol, methanol, DMF or DMSO. Related to: Pimprinine CAS Number: 21200-24-8 Molecular Formula: C14H15N3O2 Molecular Weight: 257.3 |
Source: Streptomyces sp. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Indolmycin resistance of Streptomyces coelicolor A3(2) by induced expression of one of its two tryptophanyl-tRNA synthetases. Kitabatake M. et al. J. Biol. Chem. 2002, 277, 23882. 2. Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori agent. Hasuoka A. et al. Chem. Pharm. Bull. 2001, 49, 1604. 3. Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli. Bogosian G. et al. J. Bacteriol. 1983, 153, 1120.
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