Technical Data
I7650-04W
Influenza A Hemagglutinin (H1N1)
Description:
Influenza type A viruses are divided into subtypes based on the antigenic differences of two viral surface proteins, hemagglutinin (H) and neuraminidase (N). On infection of the respiratory tract, the hemagglutinin molecule binds to sialic acid-containing receptors on the epithelial cells resulting in endocytosis. Once the virus has been engulfed, the hemagglutinin allows the viral membrane to fuse with the endosomal membrane. Neuraminidase functions to aid viral release from host cells by cleaving terminal sialic acid residues from carbohydrate moieties on the cell surface.Subtype antigenic variations result from a process known as antigenic drift whereby these surface proteins constantly mutate in order to evade the host immune responce. Subtype A(H1N1) was the cause of Spanish flu that killed approximately 500,000 people between 1918-1919.

Applications:
Suitable for use in Immunofluorescence. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG110D260Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Influenza blend
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.09% sodium azide
Specificity:
Recognizes Influenza A H1 antigen and reacts with the H1N1 stain, A/Taiwan/1/86.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.