Technical Data
Insig1, NT (Insulin-induced gene 1 protein, INSIG-1, CL6, CL-6, MGC1405)
INSIG1 is an insulin-induced protein. This protein encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
Synthetic peptide selected from the N-terminal region of human INSIG1 (KLH).
Purified by immunoaffinity chromatography.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes human INSIG1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Smith,E.M.,, J. Lipid Res. 51(4), 701-708 (2010). 2. Liu,X.,, Atherosclerosis 208(2), 421-426 (2010).