		Technical Data
I7661-15Y	IMP-3, ID (Insulin-like Growth Factor 2 mRNA Binding Protein 3, IGF2 mRNA-binding Protein 3, IGF2BP3, IMP3, IGF-II mRNA-binding Protein 3, CT98, KH Domain-containing Protein Overexpressed in Cancer, hKOC, KOC1, VICKZ Family Member 3, VICKZ3)

Description:
IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. This protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the Center region of human IMP3 (KLH).

Purity:

Purified by ammonium sulfate precipitation.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human IMP3.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Kobel,M., et.al.,Mod. Pathol. 22(3), 469-475 (2009).