Technical Data
I7661-16G7
Insulin-Like Growth Factor Binding Protein 2, Recombinant, Human (IGFBP2, BP2, IBP2)
5ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

Source:
yeast

Biological Activity:
Binding activity of human IGF-BP 2 is under investigation by the inhibition activity of both IGF I and II.

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
31kD
Source: yeast
Purity: Purified. 90% pure by SDS gel electrophoresis.
Concentration: As reported
Form: Supplied as a lyophilized powder in PBS

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1.Kiefer, M.C., Schmid, C., Waldvogel, M., Sclapfer, I., Futo, E., Maziarz, F.R., Green, K., Barr, P.J. and Zapf, J. (1992) The Journal of Biological Chemistry, Vol 267, No 18, 12692-12699 2. Rechler M.M. and Brown A.L. (1992) Growth Regulation, 2, 55. 3. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ., pages 311-415

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.