		Technical Data
I7661-75B	Interferon alpha 2b, aa24-188, Recombinant, Human (IFNa2, IFNa2b)	100ug

Growth Factors, Cytokines

Storage: -20°CShipping: Blue Ice

Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon a-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon a-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Recombinant protein corresponding to aa24-188 of human IFNA2 expressed in E. coli (NP_000596).

AA Sequence:
MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
19.4kD

Source: E. coli
Purity: 95% (SDS-PAGE)
Concentration: ~1mg/ml
Form: Supplied as a liquid in PBS, pH 7.4.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

1. Mire-Sluis, A.R., et al., J. Immunol. Methods. 195: 55-61 (1996). 2. Rubinstein, S., et al., J. Virol. 37: 755-758 (1981).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.