Technical Data
I7661-77A
IFNAR2, ID (Interferon alpha/beta Receptor 2, IFN-R-2, IFN-alpha Binding Protein, IFN-alpha/beta Receptor 2, Interferon alpha Binding Protein, Type I Interferon Receptor 2, IFNABR, IFNARB)
Description:
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to SYDSPDYTDESCT from the internal region of human IFNAR2.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human IFNAR2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.