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Technical Data |
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I7661-90 |
Interferon alpha 1, Recombinant, Human (IFNa) |
100ug |
| Growth Factors, Cytokines | Storage: -70°CShipping: Dry Ice |
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Interferon-alpha is cytokines that are widely known to induce potent anti-viral activity . Interferon-alpha exerts a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Recombinant human Interferon-alpha was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Molecular Weight: 19.5kD (167 amino acids) Sequence: MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM/RSLSLSTNLQ ERLRRKE Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 19.5 kD |
Source: Human Purity: 95% by SDS PAGE Concentration: ~1mg/ml Form: Supplied as a liquid in PBS, pH 7.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Goeddel DV, et al. (1981) Nature, 290(5801): 20-6 2. Mire-Sluis, A.R., et al.(1996) J. Immunol. Methods.195: 55-61 3. Rubinstein, S., et al.(1981) J. Virol. 37: 755-758
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