Technical Data
I7661-90
Interferon alpha 1, Recombinant, Human (IFNa)
100ug
Molecular Biology Storage: -70CShipping: Dry Ice
Interferon-alpha is cytokines that are widely known to induce potent anti-viral activity . Interferon-alpha exerts a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases.

Recombinant human Interferon-alpha was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Molecular Weight: 19.5kD (167 amino acids)

Sequence:
MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM/RSLSLSTNLQ ERLRRKE

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
19.5 kD
Source: Human
Purity: 95% by SDS PAGE
Concentration: ~1mg/ml
Form: Supplied as a liquid in PBS, pH 7.4

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Goeddel DV, et al. (1981) Nature, 290(5801): 20-6 2. Mire-Sluis, A.R., et al.(1996) J. Immunol. Methods.195: 55-61 3. Rubinstein, S., et al.(1981) J. Virol. 37: 755-758

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.