Technical Data
I7662-11C
Interferon beta, Recombinant, Mouse, aa22-182, His-Tag (Ifb, IFN-beta, IFNB)
100ug
Molecular Biology Storage: -70CShipping: Dry Ice
Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis.

Source:
Recombinant corresponding to aa22-182 from mouse Interferon beta expressed in E. coli.

Molecular Weight: 22.0kD (182aa)

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN

Storage and Stability:
Aliquot to avoid repeated freezing and thawing and Store at -70C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight:
22.0kD
Source: His-tagged, Recombinant, E. coli
Purity: 95% (SDS-PAGE)
Concentration: ~0.5mg/ml
Form: Supplied as liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 30% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Fierlbeck G, et al. (1992) Hautarzt. 43(1):16-21. 2. Panitch HS. (1992) Drugs. 44(6):946-62.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.