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Technical Data |
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I7662-11C |
Interferon beta, Recombinant, Mouse, aa22-182, His-tag (Ifb, IFN-beta, IFNB) |
100ug |
| Growth Factors, Cytokines | Storage: -70°CShipping: Dry Ice |
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Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis. Source: Recombinant corresponding to aa22-182 from mouse Interferon beta expressed in E. coli. Molecular Weight: 22.0kD (182aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN Storage and Stability: Aliquot to avoid repeated freezing and thawing and Store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Molecular Weight: 22.0kD |
Source: His-tagged, Recombinant, E. coli Purity: 95% (SDS-PAGE) Concentration: ~0.5mg/ml Form: Supplied as liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 30% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Fierlbeck G, et al. (1992) Hautarzt. 43(1):16-21. 2. Panitch HS. (1992) Drugs. 44(6):946-62.
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