Technical Data
I7662-79D
Interferon Regulatory Factor 2, aa1-113, Recombinant, Human (IRF2)
100ug
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Technical Data |
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I7662-79D |
Interferon Regulatory Factor 2, aa1-113, Recombinant, Human (IRF2) |
100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Dry Ice |
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Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Sequences: MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 15kD (133aa) |
Source: E. coli Purity: 95% by SDS PAGE. Purified by using chromatography techniques. Concentration: ~1mg/ml Form: Supplied as a liquid in 20mM Tris, pH 8.0, 1mM DTT, 10% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Harada, H., et al. (1989) Cell. 58(4):729-739. 2. Matsuyama T., et al. (1993) Cell 75(1):83-97.
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