Technical Data
I7662-79D
Interferon Regulatory Factor 2, aa1-113, Recombinant, Human (IRF2)
100ug
Molecular Biology Storage: -20CShipping: Dry Ice
Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation.

Sequences:
MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
15kD (133aa)
Source: E. coli
Purity: 95% by SDS PAGE. Purified by using chromatography techniques.
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris, pH 8.0, 1mM DTT, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Harada, H., et al. (1989) Cell. 58(4):729-739. 2. Matsuyama T., et al. (1993) Cell 75(1):83-97.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.