Technical Data
I7662-81
Interferon Regulatory Factor 1, Recombinant, Human (IRF1)
500ug
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Technical Data |
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I7662-81 |
Interferon Regulatory Factor 1, Recombinant, Human (IRF1) |
500ug |
| Growth Factors, Cytokines | Storage: 4°C/-20°CShipping: Blue Ice |
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IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques. Molecular Weight: 15kD (114 amino acids) Sequences: MGSSHHHHHH/ SSGLVPRGSH/ MPITRMRMRP/ WLEMQINSNQ/ IPGLIWINKE/ EMIFQIPWKH/ AAKHGWDINK/ DACLFRSWAI/ HTGRYKAGEK/ EPDPKTWKAN/ FRCAMNSLPD/ IEEVKDQSRN/ KGSSAVRVYR/ MLPP Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 15kD |
Source: Recombinant, Human, His-tag, E. coli Purity: 90% by SDS-PAGE Concentration: ~1mg/ml Form: Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Hochhaus A., et al. (1997) Leukemia. Jul;11(7):933-9 2. Liu J., et al. (2005) J Biol Chem. 280(26):24347-55
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