Technical Data
I7662-81
Interferon Regulatory Factor 1, Recombinant, Human (IRF1)
500ug
Growth Factors, Cytokines Storage: 4C/-20CShipping: Blue Ice
IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 15kD (114 amino acids)

Sequences:
MGSSHHHHHH/ SSGLVPRGSH/ MPITRMRMRP/ WLEMQINSNQ/ IPGLIWINKE/ EMIFQIPWKH/ AAKHGWDINK/ DACLFRSWAI/ HTGRYKAGEK/ EPDPKTWKAN/ FRCAMNSLPD/ IEEVKDQSRN/ KGSSAVRVYR/ MLPP

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
15kD
Source: Recombinant, Human, His-tag, E. coli
Purity: 90% by SDS-PAGE
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Hochhaus A., et al. (1997) Leukemia. Jul;11(7):933-9 2. Liu J., et al. (2005) J Biol Chem. 280(26):24347-55

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.