		Technical Data
I7662-91	Interferon Regulatory Protein 3, Recombinant, Human (IRF3)	500ug

Growth Factors, Cytokines

Storage: 4°C/-20°CShipping: Blue Ice

Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. Recombinant human IRF3 was expressed in E. coli and purified by using conventional chromatography techniques.

Sequence:
MGTPKPRILP/ WLVSQLDLGQ/ LEGVAWVNKS/ RTRFRIPWKH/ GLRQDAQQED/ FGIFQAWAEA/
TGAYVPGRDK/ PDLPTWKRNF/ RSALNRKEGL/ RLAEDRSKDP/ HDPHKIYEFV/ NS

Storage and Stability:
May be stored at 4°C for short-term only. For lo.ng-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer

Molecular Weight:
13.0 kD

Source: Recombinant, Human, E. coli
Purity: 95% by SDS PAGE
Concentration: ~1mg/ml
Form: Supplied as a liquid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

1. Pietila TE et al., J Immunol. (2007) 178(1):253-61 2. DeFilippis VR et al., J Virol., (2006) 80(2):1032-7

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.