Technical Data
IRF8, CT (Interferon Regulatory Factor 8, IRF-8, Interferon Consensus Sequence-binding Protein, ICSBP, IRF8, ICSBP1)
Abs to Interferon Storage: -20CShipping: Blue Ice
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
Purity: Purified by ammonium sulfate precipitation.
Immunogen: Synthetic peptide selected from the C-terminal region of human IRF8 (KLH).
Specificity: Recognizes human IRF8.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1.McGough,J.M., Mol. Cancer Res. 6(12), 1841-1851 (2008). 2.Tshuikina,M., Exp. Hematol. 36(12), 1673-1681 (2008). 3.Martinez,A., Am. J. Surg. Pathol. 32(8), 1190-1200 (2008).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.