Technical Data
I7663-01A3
Interleukin 1 alpha, Recombinant, Human (IL-1a, Hematopoietin-1, Lymphocyte-activating Factor, LAF, Endogenous Pyrogen, Leukocyte Endogenous Mediator, LEM, Mononuclear Cell Factor, MCF)
10ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1 is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation.

Recombinant IL-1a, 113-271aa, Human, His-tagged, Recombinant, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 22.4kD (197aa)

Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA PFSFLSNVKY NFMRIIKYEF
ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT
AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL
AGGPPSITDF QILENQA

Molecular Weight:
22.4kD (197aa)
Source: Recombinant IL-1a, 113-271aa, Human, His-tagged, Recombinant, was expressed in E. coli
Purity: 90% as determined by SDS-PAGE
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris-HCl pH 7.5, 10% glycerol

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
General References:
1. Misener VL., et al. (2008). Neuropsychobiology. 58(2):71-80
2. Sarkar O., et al. (2008). Biol Reprod. 78(3):445-54

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.