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Technical Data |
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I7663-07B |
Interleukin 1 beta, aa118-269, Recombinant, Mouse, His tag (IL1b, IL-1 beta, Catabolin, Hematopoietin 1, H1, IFN beta Inducing Factor, IL1F2, LAF, OAF, Osteoclast Activating Factor, Preinterleukin beta, Pro Interleukin 1 beta) |
100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Murine IL1 beta, 118-269 aa, His tagged, Recombinant, E. coli. NCBI Accession No.: NP_032387 IL-1 beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1 beta is required for tumor growth, metastasis, and angiogenesis in several animal models. Murine IL1 beta, 118-269 aa, His tagged, purified by using conventional chroma- tography techniques. AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 21kD |
Source: Recombinant, E. coli Purity: 90% by SDS PAGE Concentration: ~1mg/ml Form: Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Saijo Y, et al, (2002) J. Immunol. 169:469–475. 2.Torisu H, et al, (2000) J. Cancer. 85:182–188.
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