Technical Data
I7663-22
Interleukin 1 beta, Recombinant, Mouse (IL-1b)
2ug
10ug
10ug
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Technical Data |
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I7663-22 |
Interleukin 1 beta, Recombinant, Mouse (IL-1b) |
2ug 10ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: RT |
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Interleukin-1 beta (IL-1beta) is a potent immunomodulator which mediates a wide range of immune and inflammatory responses, including the activation of B and T cells. Murine IL-1b is a 17.5kD protein containing 153 amino acid residues. Biological Activity: Murine IL-1b is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of murine D10S cells is 0.002ng/ml, corresponding to a specific activity of 5x10e8 units/mg. Responding Cells (partial list): Leukocytes. AA Sequence: MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O containing a carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 17.5kD |
Source: Murine, recombinant, produced in E. coli Purity: ~ 98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug Form: Supplied as a lyophilized powder from sodium citrate, pH 4.0. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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