Technical Data
I8426-02A
Interleukin 4, Recombinant, Human (IL-4, B Cell Stimulatory Factor 1, BSF1, Binetrakin, HCGF, Hodgkin's Cell Growth Factor, IA Inducing Factor, Lymphocyte Stimulatory Factor 1, Macrophage Fusion Factor, Mast Cell Growth Factor 2, MCGF2, MFF, MGC79402, Pit
5ug
20ug
100ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
Interleukin (IL)-4, produced primarily by CD4(+) T cells is an immunomodulatory cytokine, which can inhibit the growth of tumor cells.IL-4 has been known as a Th2 cytokine and can act on B cells, T cells, and monocytes.Interleukin (IL)-4 exhibits antitumor activity in rodent experimental gliomas, which is likely mediated by the actions of IL-4 on a variety of immune cells present in and around the tumor masses.


Biological Activity: Recombinant Human Interleukin-4 is fully biologically active when compared to standard. The ED50 as measured by CD23 receptor binding on human proliferal macrophages at a concentration of 1.8ng/ml.

AA Sequence:
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute with sterile ddH2O. Add 0.1% BSA or HSA for long term storage. Aliquot and store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
15kD
Source: Recombinant, human, E. coli
Purity: 98% as determined by RP-HPLC; Reducing and non-reducing SDS-PAGE. Endotoxin: 0.1EU/ug (LAL).
Form: Supplied as a lyophilized powder. Reconstitute with sterile ddH2O, carrier protein to a concentration of 0.1mg/ml, which can be further diluted into other aqueous solutions.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.