Technical Data
I8428-23P
Interleukin 6 (IL-6)
Description:
IL-6 is a cytokine with a wide variety of biological functions. It plays an essential role in the final differentiation of B-cells into Ig-secreting cells. It induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.

Applications:
Suitable for use in Immunohistochemistry, Intracellular staining, Western Blots, Neutralization and ELISA as a coating antibody. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Myeloma/Fusion:
Rat spleen cells fused with P3X63-AG8.653 myeloma

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG14H171Affinity Purified
SizeStorageShippingSourceHost
500ug-20CBlue IceMouseRat
Concentration:
~1mg/ml
Immunogen:
Recombinant mouse IL-6
Purity:
Purified by Protein A/G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide. Dilute further with PBS, 1% BSA and 0.1% sodium azide.
Specificity:
Recognizes natural and recombinant mouse IL-6.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Abrams JS, et al. 1992. Immunological Review. 127:5-24. 2. Segura M, et al. 1999. Infection and Immunity 67:4646-4654. 3. Fenton RR, et al. 2002. Invest. Opthamol. Vis. Sci. 43:737-743.