Technical Data
I8434-27A
IL12B (Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2)
Description:
Interleukin-12 (IL-12p40/IL-12B), a member of the type I cytokine receptor family, which exists as a heterodimer with the p35 subunit (IL-12p35/IL-12A) to form interleukin-12 (IL-12), and with the p19 subunit of IL-23 (IL-23p19/IL-23A), to form interleukin-23 (IL-23).
IL-12 is an important factor in the T helper cell (Th1) immune response, promotes the development and activity of activated T cells and natural killer cells (NK), induces IFN-gamma production, and enhances long-term resistance against invading pathogens, by sustaining a sufficient number of memory/effector Th1 cells.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Liver lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-QGKSKREKKDRVFTD, from the internal region of the protein sequence according to NP_002178.2.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human IL12B.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.