		Technical Data
I8434-27A	IL12B (Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2)

Description:
Interleukin-12 (IL-12p40/IL-12B), a member of the type I cytokine receptor family, which exists as a heterodimer with the p35 subunit (IL-12p35/IL-12A) to form interleukin-12 (IL-12), and with the p19 subunit of IL-23 (IL-23p19/IL-23A), to form interleukin-23 (IL-23).
IL-12 is an important factor in the T helper cell (Th1) immune response, promotes the development and activity of activated T cells and natural killer cells (NK), induces IFN-gamma production, and enhances long-term resistance against invading pathogens, by sustaining a sufficient number of memory/effector Th1 cells.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Liver lysate

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to C-QGKSKREKKDRVFTD, from the internal region of the protein sequence according to NP_002178.2.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

Specificity:

Recognizes human IL12B.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.