Technical Data
I8434-27G
IL12B, Recombinant, Human (Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2)
10ug
100ug
100ug
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Technical Data |
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I8434-27G |
IL12B, Recombinant, Human (Interleukin-12 Subunit beta, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40kD Subunit, CLMF p40, IL-12 Subunit p40, NK Cell Stimulatory Factor Chain 2, NKSF2) |
10ug 100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation. Source: Recombinant corresponding to aa23-328 from mature human IL12B fused to 6x His-tag at N-terminal, expressed in E. coli. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Source: E. coli Purity: ~95% (SDS-PAGE) Concentration: As reported Form: Supplied as liquid. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Gately, M.K. et al. (1998) Annual Rev. Immunol. 16: 495-521.
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