Technical Data
IL17A, Recombinant, Human (Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8, CTLA8, IL17)
Molecular Biology Storage: -20CShipping: Blue Ice
Interleukin 17A (IL-17A) is the original member of the IL-17 family of structurally related cytokines (IL-17 A to IL-17F) that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17A is a pro-inflammatory cytokine produced primarily by T cells and is commonly associated with the allergic response facilitating the release of other cytokines, chemokines and prostaglandins from a variety of cell types. IL-17A exists in vitro as a homodimer of two 132aa chains.

Recombinant corresponding to aa24-155 from human IL-17A monomer coding sequence, fused to 6x His-tag at N-terminal, expressed in E. coli.

Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistohemistry, Immunoassays, Development of Rapid tests and other immunoassay. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: E. coli
Purity: ~95% (SDS-PAGE)
Concentration: As reported
Form: Supplied as liquid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Gaffen S.L. et al., (2006) Vitam. Horm. 74: 255-282.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.