Technical Data
I8442-42Q
IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor alpha-inducing Factor, IL32, NK4, TAIF)
Description:
IL-32 is the name given to the NK4 transcript first reported in IL-2 activated T lymphocytes and natural killer cells. IL-32 induces the degradation of inhibitory kappaB and phosphorylation of mitogen activated protein p38 and has a possible role in inflammatory:autoimmune diseases like chronic obstructive pulmonary disease, Crohn's disease and psoriasis. The protein activates typical cytokine signal pathways of nuclear factor-kappa B (NF-kappaB) and p38 mitogen-activated protein kinase. The protein contains a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. It is selectively expressed in human lymphocytes. The gene encoding human IL-32 protein is localized on chromosome 16p13.3.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Synthetic peptide corresponding to aa210-227 ([BLAST]QSYGAPRGDKEELTPQKC[BLAST]) of human IL-32.
Purity:
Serum
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity:
Recognizes human IL-32.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kim, SH. et al. Immunity. 22:131-142 (2005).