Technical Data
J8009-04H
Junctional Adhesion Molecule 1 (JAM 1, JAM-1, JAM1, CD321, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAM-A, JAMA, JCAM, KAT, Platelet Adhesion Molecule 1, PAM-1, PAM1, Platelet F11 Receptor, UNQ264/PRO301)
Description:
Applications:
Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:10.
Western Blot: 1:10
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1M.Ab.F11Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanMouse
Concentration:
~0.1mg/ml
Immunogen:
Human platelet F11-Receptor (F11R) is a cell adhesion molecule (CAM).
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.1% BSA.
Specificity:
Recognizes human platelet F11-Receptor.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kornecki, E et al; Activation of human platelets by a stimulatory monoclonal antibody. J Biol Chem 1990, 265: 10042 2. Walkowisk B et al; Preferred use of primary radiolabeled anti-platelet monoclonal antibodies. Comparison of immunoblotting methods for the analysis of functional domains on human platelets. Thromb Res 1992, 68: 323 3. Naik, U et al; Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the Fc gamma RII receptor. Biochem J 1995, 310: 155 4. Wang, F et al; Stimulatory antibody-induced activation and selective translocation of protein kinase C isoenzymes in human platelets. Biochem J 1995, 311: 401
5. Sobocka, M et al; Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation. Blood 2000, 95: 2600 6.Babinska, A et al; Two regions of the human platelet F11-receptor (F11R) are critical for platelet aggregation, potentiation and adhesion. Thromb Haemost 2002, 87: 712.