Technical Data
Junctional Adhesion Molecule 1 (JAM 1, JAM-1, JAM1, CD321, ESTM33, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAM-A, JAMA, JCAM, Jcam1, Ly106, Platelet Adhesion Molecule 1, PAM-1, PAM1, Platelet F11 Receptor)
Junctional adhesion molecule-1 (JAM-1) also known as the mouse platelet F11-Receptor (F11R) is a cell adhesion molecule (CAM). JAM-1 is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-1 belongs together with JAM-2 and JAM-3 to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-1 plays a role in platelet aggregation, secretion, adhesion and spreading.

Suitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:10.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgGBV12Affinity Purified
100ug-20CBlue IceMouseRat
Mouse Junctional Adhesion Molecule 1.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Recognizes mouse Junctional Adhesion Molecule 1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bazzoni, G et al; Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem 2000, 275: 20520.