Technical Data
J8009-05A
Junctional Adhesion Molecule 1, CT (Junctional Adhesion Molecule A, JAM-A, JAM-1, Platelet Adhesion Molecule 1, PAM-1, CD321, Platelet F11 Receptor, F11R, JAM1, JCAM, F11R, UNQ264/PRO301)
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Technical Data |
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J8009-05A |
Junctional Adhesion Molecule 1, CT (Junctional Adhesion Molecule A, JAM-A, JAM-1, Platelet Adhesion Molecule 1, PAM-1, CD321, Platelet F11 Receptor, F11R, JAM1, JCAM, F11R, UNQ264/PRO301) |
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Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, F11R can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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