Technical Data
K0005-11C
Kallikrein 8 (Kallikrein-8, KLK8, hK8, HNP, Neuropsin, NP, NRPN, Ovasin, PRSS19, Serine Protease TADG-14, Serine Protease 19, Tumor-associated Differentially Expressed Gene 14 Protein, TADG14, UNQ283/PRO322, EC 3.4.21.118, Kallikrein-related Peptidase 8)
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq]

Applications:
Suitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a11C330Affinity Purified
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Recombinant protein corresponding to aa97-205 of human KLK8.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Specificity:
Recognizes human KLK8.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.