		Technical Data
K0090-09B	Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)

Description:
Useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Immunoglobulin bearing Kappa light chains are present on about 60% of normal B lymphocytes.

Applications:
Suitable for use in Turbidimetry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Recommended Secondary Antibodies:
Rabbit Anti Goat IgG (Fc) FITC, HRP

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab	IgG		Serum

Size		Storage	Shipping	Source	Host
1ml		-20°C	Blue Ice	Human	Goat

Concentration:

As reported

Immunogen:

Purified human kappa light chains.

Purity:

Serum.

Form

Supplied as a liquid in TBS, pH 7.4, 0.09% sodium azide.

Specificity:

Recognizes the Human kappa immunoglobulin light chain which comprises approximately 60% of light chains in the human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.