Technical Data
K0090-09B
Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)
Description:
Useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Immunoglobulin bearing Kappa light chains are present on about 60% of normal B lymphocytes.

Applications:
Suitable for use in Turbidimetry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Recommended Secondary Antibodies:
Rabbit Anti Goat IgG (Fc) FITC, HRP

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
1ml-20°CBlue IceHumanGoat
Concentration:
As reported
Immunogen:
Purified human kappa light chains.
Purity:
Serum.
Form
Supplied as a liquid in TBS, pH 7.4, 0.09% sodium azide.
Specificity:
Recognizes the Human kappa immunoglobulin light chain which comprises approximately 60% of light chains in the human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.