Technical Data
K0090-21
Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)
Description:
Useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Immunoglobulin bearing Kappa light chains are present on about 60% of normal B lymphocytes.

Applications:
Suitable for use in ELISA and Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a8L511
SizeStorageShippingSourceHost
200ug-20°CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Mixture of light chains of human immunoglobulin.
Purity:
As reported
Form
Supplied as a liquid in PBS, pH 7.2.
Specificity:
Specific for independent constantly expressed epitope of kappa chain. Reacts with free and heavy chain-associated kappa chains. Species Crossreactivity: Crossreacts with Human. Not yet tested in other species.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.