Technical Data
KHSRP (KH Type-splicing Regulatory Protein, KSRP, Far Upstream Element-binding Protein 2, FUSE-binding Protein 2, FBP2, FUBP2, MGC99676, p75)
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (FFPE): 5ug/ml. Requires HIER using sodium citrate buffer pH 6.0
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgG2b,k4C10Affinity Purified
50ug-20CBlue IceHumanMouse
As Reported
Patrial recombinant protein corresponding to aa151-240 from human KHSRP with GST tag (NP_003676). MW of the GST tag alone is 26kD.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.4.
Recognizes human KHSRP.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.