Technical Data
K1759-20B
KIF4A (Chromosome-associated Kinesin KIF4A, Chromokinesin-A, KIF4)
Description:
KIF4A is required for mitotic chromosomal positioning and bipolar spindle stabilization. It is located in the nucleus and is associated with mitotic chromosomes. It is highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Synthetic peptide corresponding to aa1199-1213 (EYQENKAPGKKKKRA) of human Kif4.
Purity:
Serum.
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity:
Recognizes human Kif4. Species sequence homology: mouse, rat, canine, bovine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Zhu,C. and Jiang,W. Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis Proc. Natl. Acad. Sci. U.S.A. 102 (2), 343-348 (2005). 2. Kurasawa,Y., Earnshaw,W.C., Mochizuki,Y., Dohmae,N. and Todokoro,K. Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J. 23 (16), 3237-3248 (2004).