Technical Data
L1185-05C
Lambda Light Chain (Bence Jones Protein, BJP, Constant Region of Lambda Light Chains, Ig Lambda Chain C Regions, IGLC, IGLC1, IGLC2, IGLC3, Immunoglobulin Lambda Constant 1, Mcg Marker, Paraprotein)
Description:
This antibody stains B cell follicles in human lymphoid tissues. The mantle zone shows a mosaic pattern of labeling while the germinal centers show a coarse meshwork pattern of staining. Lambda light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non-Hodgkin's lymphomas.

Cellular Localization: Cytoplasm

Positive Control: Tonsil

Applications:
Suitable for use in Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a,k8L546Affinity Purified
SizeStorageShippingSourceHost
6ml-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Purified human IgG myeloma proteins covalently linked to polyaminostyrene micro beads.
Purity:
Purified by Protein A affinity chromatography.
Form
Sodium Azide; PBS
Specificity:
Species Crossreactivity: Crossreacts with Human. Does not crossreact with Rat. Not yet tested in other species.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Jefferis R et al. Evaluation of monoclonal antibodies having specificity for human IgG subclasses: results of the 2nd IUIS/WHO collaborative study. Immunol Lett 31:143-68 (1992). Reimer CB et al. Evaluation of thirty-one mouse monoclonal antibodies to human IgG epitopes. Hybridoma 3:263-75 (1984).