Technical Data
L2623-01C
LOX-1 (CLEC8A, hLOX-1, Lectin-like Oxidized LDL Receptor 1, Lectin-like OxLDL Receptor 1, Lectin-type Oxidized LDL Receptor 1, LOX1, LOX-1, Oxidized Low Density Lipoprotein (Lectin-like) Receptor 1, Oxidized Low-density Lipoprotein Receptor 1, Ox-LDL Rece
Description:
LOX-1 is a type II transmembrane protein belonging to the C-type lectin family. It is highly expressed on endothelial cells and functions as an endocytosis receptor for atherogenic oxidized LDL. Soluble LOX-1 can be generated from the transmembrane protein by proteolytic cleavage.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA (capture): 2-8ug/ml
Optimal dilutions to be determined by the researcher.

Hybridoma:
Mouse myeloma with B cells obtained from a rat immunized with purified, NS0-derived, recombinant mouse LOX-1.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2b9i234Affinity Purified
SizeStorageShippingSourceHost
500ug-20CBlue IceMouseRat
Concentration:
~0.5mg/ml
Immunogen:
NS0-derived, recombinant mouse LOX-1 (aa60-363)
Purity:
Purified by Protein A/G affinity chromatography.
Form
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
Specificity:
Recognizes mouse LOX-1. No crossreactivity was observed with recombinant human LOX-1 or human LDL, HDL or VLDL.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.