		Technical Data
L2623-01C	LOX-1 (CLEC8A, hLOX-1, Lectin-like Oxidized LDL Receptor 1, Lectin-like OxLDL Receptor 1, Lectin-type Oxidized LDL Receptor 1, LOX1, LOX-1, Oxidized Low Density Lipoprotein (Lectin-like) Receptor 1, Oxidized Low-density Lipoprotein Receptor 1, Ox-LDL Rece

Description:
LOX-1 is a type II transmembrane protein belonging to the C-type lectin family. It is highly expressed on endothelial cells and functions as an endocytosis receptor for atherogenic oxidized LDL. Soluble LOX-1 can be generated from the transmembrane protein by proteolytic cleavage.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA (capture): 2-8ug/ml
Optimal dilutions to be determined by the researcher.

Hybridoma:
Mouse myeloma with B cells obtained from a rat immunized with purified, NS0-derived, recombinant mouse LOX-1.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Mab	IgG2b	9i234	Affinity Purified

Size		Storage	Shipping	Source	Host
500ug		-20°C	Blue Ice	Mouse	Rat

Concentration:

~0.5mg/ml

Immunogen:

NS0-derived, recombinant mouse LOX-1 (aa60-363)

Purity:

Purified by Protein A/G affinity chromatography.

Form

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.

Specificity:

Recognizes mouse LOX-1. No crossreactivity was observed with recombinant human LOX-1 or human LDL, HDL or VLDL.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.