Technical Data
Luzopeptin A (Antibiotic BBM-928A)
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Luzopeptin is a member of the echinomycin (quinomycin A) class of antitumor and antibiotic agents that act by formation of a stable DNA complex by bis-intercalation. Luzopeptin A has also been shown to be a potent inhibitor of HIV-1 reverse transcriptase.

DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water

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Source: Actinomadura sp.(luzonensis)
Purity: >99%
Form: Tan solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. BBM-928, a new antitumor antibiotic complex I. Production, isolation, characterization and antitumor activity. Ohkuma, H. et al., J. Antibiot. 1980, 33, 1087. 2. Screening for inhibitors of avian myeloblastosis virus reverse transcriptase and effect on the replication of AIDS virus. Inouye Y.J. Antibiot. 1987, 40, 100. 3. Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening. Leroy J.L. et al. Biochemistry. 1992, 31, 1407.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.