Technical Data
L7715-35D
Ly-6C (Lymphocyte Antigen 6 Complex, Locus C)
Description:
Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.

Applications:
Suitable for use in Flow Cytometry, Western Blot, T-cell activation and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2cHK1.4Supernatant
SizeStorageShippingSourceHost
250ul-20CBlue IceMouseRat
Concentration:
Not determined.
Immunogen:
Murine Ly-6C (T-cell activating).
Purity:
Tissue Culture Supernatant
Form
Supplied as a liquid.
Specificity:
Recognizes extracellular domain of Murine Ly-6C (T-cell activating).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Havran (1988) J Immunol 140(4): 1034; 2. Johnson (1993) J Immunol 151(6): 2986; 3. Lancki (1995) Immunol Rev 146:117