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Technical Data |
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M1202-32D |
Macrophage Inflammatory Protein 1 beta, Recombinant, Human (CCL4, Chemokine (C-C Motif) Ligand 4, ACT2, Act-2, ACT-2, AT744.1, G-26, G-26 T-lymphocyte-secreted Protein, H400, HC21, LAG1, LAG-1, Lymphocyte Activation Gene 1 Protein, MGC104418, MGC126025, M |
10ug |
| Growth Factors, Cytokines | Storage: -70°CShipping: Blue Ice |
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Macrophage Inflammatory Protein-1( (MIP-1& alpha) is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1& alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1& alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1& alpha is composed of 69 aa residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1& alpha is 60% homologous with human MIP-1& alpha. Source: yeast Biological Activity: The biological activity of recombinant human MIP-1&# alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 8kD |
Source: yeast Purity: Purified. 95% pure by SDS gel electrophoresis. Concentration: As reported Form: Supplied as a lyophilized powder in PBS Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Nathan, C.F. (1987)J. Clin. Invest. 79:31 2. Tekamp-Olson. P. et al. (1990) J. Exp. Med. 172:911 3. Wolpe S.D. et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:612
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