Technical Data
Macrophage Inflammatory Protein 1 beta, Recombinant, Human (CCL4, Chemokine (C-C Motif) Ligand 4, ACT2, Act-2, ACT-2, AT744.1, G-26, G-26 T-lymphocyte-secreted Protein, H400, HC21, LAG1, LAG-1, Lymphocyte Activation Gene 1 Protein, MGC104418, MGC126025, M
Molecular Biology Storage: -70CShipping: Blue Ice
Macrophage Inflammatory Protein-1( (MIP-1& alpha) is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1& alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1& alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1& alpha is composed of 69 aa residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1& alpha is 60% homologous with human MIP-1& alpha.


Biological Activity:
The biological activity of recombinant human MIP-1&# alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Source: yeast
Purity: Purified. 95% pure by SDS gel electrophoresis.
Concentration: As reported
Form: Supplied as a lyophilized powder in PBS

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Nathan, C.F. (1987)J. Clin. Invest. 79:31 2. Tekamp-Olson. P. et al. (1990) J. Exp. Med. 172:911 3. Wolpe S.D. et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:612

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.