Technical Data
M1499-15F
MAD2L1 (Mitotic Spindle Assembly Checkpoint Protein MAD2A, MAD2-like 1, MAD2-like Protein 1, Homolog of MAD2 (S. cerevisiae), HsMAD2, Human Mitotic Feedback Control Protein Madp2, MAD2, MAD2 Mitotic Arrest Deficient-like 1, MAD2A, MD2L1, Mitotic Arrest De
Description:
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide C-KVNSMVAYKIPVND, representing the C-Terminus of the human protein according to NP_002349.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
Specificity:
Species Crossreactivity: Tested: Expected from sequence similarity: Human, Mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Li Y, Benezra R. Identification of a human mitotic checkpoint gene: hsMAD2. Science. 1996 Oct 11;274(5285):246-8.
PMID: 8824189