Technical Data
M1499-15H
MAD2L1 (Mitotic Spindle Assembly Checkpoint Protein MAD2A, HsMAD2, Mitotic Arrest Deficient 2-like Protein 1, MAD2-like Protein 1, MAD2)
Description:
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:3000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ul-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Recombinant corresponding to aa1-174 from human MAD2.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in 0.1M Tris-glycine, pH 7, 0.01% thimerosal, 20% glycerol.
Specificity:
Recognizes human MAD2L1. Species sequence homology: mouse (94%) and rat (95%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.