Technical Data
M1727-50
MAEL, CT (Protein Maelstrom Homolog, CT128, FLJ14904, RP11-102C16.1)
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Technical Data |
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M1727-50 |
MAEL, CT (Protein Maelstrom Homolog, CT128, FLJ14904, RP11-102C16.1) |
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Description: MAEL plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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