Technical Data
M2346-16
MAP1LC3A, aa1-120, Recombinant, Human (Microtubule-associated Proteins 1A/1B Light Chain 3A, Autophagy-related Protein LC3 A, Autophagy-related Ubiquitin-like Modifier LC3 A, MAP1 Light Chain 3-like Protein 1, MAP1A/MAP1B Light Chain 3 A, MAP1A/MAP1B LC3
100ug
Molecular Biology Storage: -20CShipping: Blue Ice
Microtubule-associated proteins 1A/1B light chain 3A isoform a, also known as MAP1LC3A, is one of the light chain subunits and can associate with either MAP1A or MAP1B. It plays critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

Source:
Recombinant corresponding to aa1-120 of human MAP1LC3A protein, fused to His-tag at C-terminus, expressed in E.coli.

AA Sequence:
MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE QEKDEDGFLY MVYASQETFG LEHHHHHH

Molecular Weight: 15.1kD (128aa) confirmed by MALDI-TOF

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
15.1kD
Source: E.coli
Purity: ~95% (SDS-PAGE).
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 20% glycerol, 0.1M sodium chloride.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Schoenfeld TA., et al. (1989) J Neurosci. 9(5):1712-30. 2. Mann., et al. (1996) J Neurosci Res. 43:535-544.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.