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Technical Data |
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M2750-18B4 |
MCP4, aa24-98, Recombinant, Human (Macrophage/Monocyte Chemotactic Protein 4, Monocyte Chemotactic Protein 4, MCP-4, C-C Motif Chemokine 13, Chemokine (C-C Motif) Ligand 13, CCL13, CK-beta-10, CKb10, MGC17134, Monocyte Chemoattractant Protein 4, NCC1, NCC |
10ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-a. Source: Recombinant corresponding to aa24-28 of human CCL13 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT Molecular Weight: 10.8kD (96aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 10.8kD |
Source: E.coli Purity: ~90% (SDS-PAGE). Form: Supplied as a liquid in PBS, pH7.4, 10% glycerol, 0.1M sodium chloride, 1mM DTT. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Garcia-Zepeda EA, et al. (1996) J Immunol. 157:5613-5626.
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