Technical Data
M2762-02
MEC, Recombinant, Mouse (CCL28, Mucosae Associated Epithelial Chemokine, Chemokine (C-C motif) ligand 28)
100ug
Molecular Biology Storage: -20CShipping: Blue Ice
CCL28, also known as chemokine (C-C motif) ligand 28 or mucosae-associated epithelial chemokine(MEC), belongs to the subfamily of small cytokine CC proteins. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. This chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. Recombinant CCL28 protein, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques.

Source:
Recombinant human CCL28, aa23-127 His-tagged, expressed in E. coli

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MILPIASSCC TEVSHHISRR LLERVNMCRI QRADGDCDLA AVILHVKRRR ICVSPHNHTV KQWMKVQAAK KNGKGNVCHR KKHHGKRNSN RAHQGKHETY GHKTPY

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
14.3kD
Source: E.coli
Purity: ~90% by SDS-PAGE Purified by immunoaffinity chromatography.
Concentration: ~1mg/ml
Form: Supplied as liquid in 10mM Sodium Citrate, pH3.5, 10% Glycerol

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.