Technical Data
M2825-15K
MDR1 (Multidrug Resistance Protein 1, ATP-binding Cassette Sub-family B Member 1, P-glycoprotein 1, CD243, ABCB1, PGY1)
Description:
ABCB1/MDR1/P Glycoprotein is an ATP dependent transporter that mediates efflux of chemotherapeutic agents from the intracellular milieu. P Glycoprotein has also been associated with volume-regulated chloride channel activity and basal to apical transendothelial migration of mononuclear phagocytes.

Applications:
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:10,000-1:50,000
Western Blot: 1:200-1:2000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to aa262-277 from human ABCB1 (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
Specificity:
Recognizes human ABCB. Species sequence homology: Canine, monkey, mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.