Technical Data
M2825-19A
ABCC4, CT (Multi-specific Organic Anion Transporter B, MOAT-B, MRP/cMOAT-related ABC Transporter, ATP-binding Cassette Sub-family C Member 4, Multidrug Resistance-associated Protein 4, MRP4)
Description:
ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the C-terminal region of human ABCC4 (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human ABCC4.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998). 2.Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002). 3.Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997). 4.Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008).