Technical Data
M2867-60B
Mel18 (RNF110, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, polycomb group ring finger 2)
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Technical Data |
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M2867-60B |
Mel18 (RNF110, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, polycomb group ring finger 2) |
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Description: Polycomb group ring finger 2, also known as PCGF2, is a transcriptional repressor. Polycomb group (PcG) of genes were first identified in Drosophila whereby these genes were required to sustain the stable repression of Hox cluster genes during development. Studies have shown that PCGF2 forms multimeric protein complexes associated with chromatin. In addition, PCGF2 may play a role in cell proliferation and/or neural cell development. PCGF2 is widely expressed in placenta, lung, and kidneys but expressed very little in skeletal muscle, liver, and pancreas. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human lung tissue lysate Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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