Technical Data
M3101
Methotrexate ((+)-Amethopterin, 4-Amino-10-methylpteroylglutamic Acid, Methylaminopterin, 4-Amino-10-methylfolic acid, MTX)
100mg
500mg
1g
Biochemicals Storage: -20CShipping: Blue Ice
Methotrexate is a folic acid antagonist and is classified medically as an antineoplastic and antirheumatic agent.

Melting Point:
183-191C

Solubility:
Alkaline water, DMSO

Method for Determining Identity:
Proton NMR Spectroscopic Analysis

TLC Conditions:
SiO2; isopropanol; Water: NH4OH; 6:2:1; Visualized with UV and AMCS; Single spot; Rf=0.4

Water Content:
~12% by elemental analysis

Specific Rotation:
+18.6 (c=1, 0.1N NaOH)

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

CAS Number:
59-05-2

Molecular Formula:
C20H22N8O5

Molecular Weight:
454.45
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.
Merck Index, 11th ed., p. 441, #2804 (1989).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.