Technical Data
M3547-32
O-Methylviridicatin (AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one)
1mg
Biochemicals Storage: 4C/-20CShipping: Blue Ice
3-O-Methylviridicatin is a metabolite produced by several species in the genus, Penicillium. Recently, 3-O-methylviridicatin was demonstrated to be a strong inhibitor of the tumor necrosis factor alpha (TNF)-induced replication of human immunodeficiency virus (HIV). Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite.

Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility

CAS Number:
6152-51-4

Molecular Formula:
C16H13NO2

Molecular Weight:
251.3
Source: Penicillium sp.
Purity: > 99% by HPLC
Form: White solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Studies in the biochemistry of microorganisms. 93. Cyclopenin, a nitrogen-containing metabolic product of Penicillium cyclopium Westling. Bracken A. et al. Biochem J. 1954, 57, 587. 2. Isolation of viridicatin from Penicillium palitans. J. Arch. Microbiol. 1970, 73, 261. 3. Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumour necrosis factor alpha-induced human immunodeficiency virus replication. Heguy A. et al. Antivir. Chem. Chemother. 1998, 9, 149.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.