Technical Data
M3895-07L
Migration Inhibitory Factor, Macrophage, Recombinant, Human (Macrophage MIF, Glycosylation-Inhibiting Factor, GIF, GLIF, MMIF)
100ug
|
Technical Data |
|
M3895-07L |
Migration Inhibitory Factor, Macrophage, Recombinant, Human (Macrophage MIF, Glycosylation-Inhibiting Factor, GIF, GLIF, MMIF) |
100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Dry Ice |
|
The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. Source: Recombinant corresponding to aa1-115 of human Macrophage MIF expressed in E. coli (NP_002406). Sequence MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA Molecular Weight: 12kD (115 aa) Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 12kD |
Source: E .coli. Purity: ~98% by SDS PAGE. Concentration: ~1mg/ml Form: Supplied as a liquid in 50mM Tris-HCl, pH 8.0, 0.5mM DTT, 10% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
1. Weiser WY., et al (1989) Proc Natl Acad Sci. 86: 7522-7526. 2. Bernhagen J., et al (1994) Biochemistry. 33: 14144-14155. 3. Richard B., (1996) FASEB J. 10: 1607-1613.
|
||