Technical Data
M4688-18D
MRP1 (Multidrug Resistance-associated Protein 1, MRP, ABC29, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 1, ABCC1, ABCC, GS-X, Leukotriene C(4) Transporter, LTC4 Transporter)
Description:
Applications:
Suitable for use in Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Western Blot. Other applications not tested.

Recommended Dilution:
Immunocytochemistry (acetone fixed): 1:20-50
Immunohistochemistry (acetone fixed frozen): 1:20
Flow Cytometry: 1:20-50
Western Blot: 1:20-50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2aMRPm5Supernatant
SizeStorageShippingSourceHost
1ml-20CBlue IceHumanMouse
Concentration:
250ug immunoglobulin/ml.
Immunogen:
Bacterial fusion protein of MRP1, containing aa986-1204 of the protein.
Purity:
Supernatant
Form
Supplied as a liquid in 1% BSA, 0.1% sodium azide.
Specificity:
Recognizes MRPm5 reacts with an internal epitope of MRP1, a 180-195kD transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cole, S., et al., 1992, Science 258, 1650-1654. 2. Flens, M., et al., 1994, Cancer Res. 54, 4557-4563.
3. Zaman, et al., 1994, Proc.Nat.Acad.Sci. USA 91, 8822-8826. 4. Schadendorf, et al, 1995, Am. J. Pathology 147, 1545-52. 5. Nooter, et al., 1995, Clin Cancer Res. 1, 1301-10. 6. Flens, M., et al., 1996, Am. J. Pathology 148, 1237-47.