Technical Data
M4688-23A
MRP3 (Multidrug Resistance-associated Protein 3, ABC31, ATP Binding Cassette Sub-family C Member 3, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 3, ABCC3, Canalicular Multispecific Organic Anion Transporter 2, CMOAT2, DKFZp686E22157, EST90757, MLP2
Description:
Applications:
Suitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and Flow Cytomtry. Other applications not tested.

Recommended Dilution:
Immunocytochemistry (acetone or formaldehyde-fixed): 1:20-1:50
Immunohistochemistry (acetone fixed frozen): 1:20
Western Blot: 1:20-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2bM3II-21Supernatant
SizeStorageShippingSourceHost
1ml-20CBlue IceMouse
Concentration:
Not determined.
Immunogen:
Raised against a bacterial fusion protein of MRP3, containing aa830-949 of the protein.
Purity:
Supernatant
Form
Supplied as a liquid, 0.7% BSA, 0.1% sodium azide.
Specificity:
Recognizes an internal epitope of MRP3, a 190-200kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. Does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kool et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5, homologs of the multidrug resistance associated protein gene (MRP1), in human cancer cell lines Cancer res. 57: 3537-3547, 1997 2. Kool et al. MRP3, an organic anion transporter able to transport anti cancer drugs. Proc. Natl. Acad. Sci. USA 96: 6915-9, 1999.